Varian TrueBeam™ System Background

The TrueBeam™ system, a linear accelerator manufactured by Varian Medical Systems, supports image-guided brain and body radiosurgery (one to five high-dose treatments) and radiotherapy (five to 40 lower-dose treatments) of almost any tumor or abnormality. TrueBeam also provides electron beam radiotherapy used for the treatment of tumors close to the surface of the body, including skin cancers.


TrueBeam system can be used for all forms of advanced external-beam radiotherapy including image-guided radiotherapy and radiosurgery (IGRT and IGRS), intensity-modulated radiotherapy (IMRT), stereotactic body radiotherapy (SBRT) and RapidArc® radiotherapy.

Treatment with Varian TrueBeam System

TrueBeam is a fully-integrated system that synchronizes imaging, patient positioning, motion management, and treatment delivery for accuracy and precision.

  • TrueBeam combines imaging, beam delivery and sophisticated RapidArc technology to accurately and precisely target tumors with great speed.

  • TrueBeam system shapes the radiation precisely to the tumor, sparing critical structures, TrueBeam delivers radiation with high precision, in increments of less than a millimeter.

  • TrueBeam rotates around the patient to deliver a prescribed radiation dose from nearly any angle.

Indications for treatment with Varian TrueBeam include:

TrueBeam can treat cancers anywhere in the body where radiation treatment is indicated, including challenging cases such as cancers in the lung, breast, abdomen, and head and neck.

Benefits for the Patient

  • Non-invasive, pain-free
  • Outpatient treatment without the risks and side-effects associated with surgery and post-operative complications
  • Treatment time is fast for more comfort
  • Shorter treatment time than conventional radiotherapy and radiosurgery
  • Radiation is shaped precisely to the tumor, sparing healthy surrounding tissue

Benefits for the Physician

  • Seamlessly integrates imaging, patient positioning, motion management, and treatment delivery for increased precision
  • Real-time imaging tools allow clinicians to "see" the tumor they are about to treat
  • Respiratory gating enables clinicians to synchronize beam delivery with patient respiration
  • Shorter treatment times mean less time for motion during dose delivery
  • Performs accuracy checks every ten milliseconds throughout the entire treatment.
  • Critical data points are measured throughout treatment to ensure the system maintains a true focal point of treatment.
3-d targeting of the tumor together with radiation treatment in one seamless progression. The two-step process usually takes 15 minutes and is as follows:

1. Image-guided Positioning: A diagnostic quality CT image is acquired on the Tomotherapy unit immediately before each treatment. This localizes a patient's anatomy (identifies the tumor size and shape) with the precision of a CT scan, resulting in a high accuracy of pretreatment positioning and tumor targeting. If the tumor's size or shape changes during treatment, radiotherapy parameters can be modified to adapt to this change.

2. TomoTherapy: After the targeting procedure has verified the target location by examining the anatomy of a patient's body, the TomoTherapy Hi·Art System uses a helical 360-degree rotating beam of radiation whereby the intensity of the radiation treatment beam is continuously modulated or controlled to conform to the shape of the tumor while minimizing radiation exposure to vital structures that may be nearby.

The TomoTherapy Hi·Art System® is capable of fractionated, stereotactic and single-dose radiotherapy, making it a very versatile technology. The TomoTherapy unit's large fieldsize capability allows it to treat areas other technologies cannot and is a significant complement to the Precision Radiotherapy's Novalis image-guided treatment unit, which treats smaller tumors of the brain, head and neck, spine, lung and liver. A patient's team of clinicians will help determine what technology is right for the individual.

Indications for treatment with TomoTherapy include:
  • Lung and Breast Cancers
  • Head & Neck Cancers
  • Gynecologic Cancers
  • Pancreatic and other Hepatobiliary tumors
  • Sarcomas
  • Rectal Cancers
  • Multiple Metastases (more than one lesion)
  • Retreatment of previous “maximally–treated” tumor
Benefits for the Patient
  • Verification of patient position prior to each therapy session via onboard CT scanner
  • Large field size
  • Radiation therapy with the precision and versatility of a CT scanner
  • Advanced Intensity Modulated Radio Therapy (IMRT): radiation beam rotates around the patient constantly
  • Minimized radiation exposure to healthy tissue
Benefits for the Physician
  • Pretreatment image verification (TomoImage™): gives the physician the confidence of knowing the size and shape of a patient's lesion each treatment day
  • Combines a highly advanced treatment planning system with advanced conformal treatment delivery
A Doctor's Opinion

Dr. David Grissell, Associate Professor of Radiation Oncology, University of Cincinnati: "Tomotherapy will offer our patients the full benefit of Intensity Modulated Radiation Therapy (IMRT) with shorter treatment times, greater accuracy and enhanced ability to avoid critical normal tissues and organs. Conventional IMRT is well established for its ability to spare normal tissues and deliver high radiation doses safely. Tomotherapy is the next generation tool for Image Guided Radiation Therapy (IGRT). It further enhances IMRT by increasing the convenience for the patient, streamlining the technical process of planning and delivering complex treatment, and ensuring millimeter accuracy by using daily CT imaging prior to each treatment."

Where is this technology being used?
  • UC Davis Cancer Center, Sacramento, California
  • Health Center, St. Louis, Missouri
  • University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin
  • Cancer Therapy and Research Center, San Antonio, Texas
  • The Methodist Hospital, Houston, Texas
  • The Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
  • M. D. Anderson Cancer Center, Orlando, Florida
  • Cromwell Hospital in London, United Kingdom
  • UCL – St. Luc University Hospital, Brussels, Belgium